바카라 게임 웹사이트Major breakthrough바카라 게임 웹사이트: Doctors unveil revolutionary cancer treatment
"CAR T is a way of 바카라 게임 웹사이트rebooting바카라 게임 웹사이트 the immune system when it has failed바카라 게임 웹사이트
"CAR T is a way of 바카라 게임 웹사이트rebooting바카라 게임 웹사이트 the immune system when it has failed바카라 게임 웹사이트
"CAR T is a way of 바카라 게임 웹사이트rebooting바카라 게임 웹사이트 the immune system when it has failed바카라 게임 웹사이트
Oklahoma doctors on Wednesday unveiled what they call a revolutionary new treatment for cancer patients.
The treatment harnesses the body바카라 게임 웹사이트s own immune cells to fight tumors, and it will be offered starting Thursday at the Stephenson Cancer Center at OU Medicine.
CAR T-cell therapy has been approved by the Food and Drug Administration. Officials said its initial use is for two different blood cancers, one affecting children and the other affecting adults.
바카라 게임 웹사이트CAR T is a major breakthrough for patients who have not improved with standard treatments,바카라 게임 웹사이트 said Dr. George Selby, director of the Transplant and Cellular Therapy Program at the Stephenson Cancer Center. 바카라 게임 웹사이트It is an immune therapy in which we바카라 게임 웹사이트re harnessing our own cells to recognize cancer cells. That바카라 게임 웹사이트s what a normal immune system does 바카라 게임 웹사이트 it acts in a surveillance capacity so that when a malignant cell arises, it is killed by our immune system. CAR T is a way of rebooting the immune system when it has failed.바카라 게임 웹사이트
CAR T initially will be used to treat advanced lymphomas in adults. In the coming months, physicians anticipate offering similar treatment for acute lymphoblastic lymphoma in children and young adults. In both cases, patients must have failed to respond to standard chemotherapy or stem cell transplant.
CAR T stands for Chimeric Antigen Receptor T-cell therapy. Patients being treated with CAR T will first have their blood collected at the Oklahoma Blood Institute in a process that is similar to a typical blood donation. T cells, a type of white blood cell involved in immunity, are filtered out and the plasma and red cells are returned to the patient. The T cells are then sent to a company that injects them with the gene for a chimeric antigen receptor, which is known to bind itself to cancer cells and activate the T cell, according to officials with the hospital.
This process allows the newly engineered T cells to recognize and attack cancer with remarkable efficiency. Once the CAR T cells are generated, they are shipped back to the Stephenson Cancer Center and given to the patient through an IV, much like a blood transfusion, officials said.
바카라 게임 웹사이트Until the advent of CAR T, if a patient바카라 게임 웹사이트s tumor came back after a stem cell transplant, their options were very limited, if they existed at all,바카라 게임 웹사이트 Selby said. 바카라 게임 웹사이트This is a major breakthrough for those patients for whom standard treatment has not been successful.바카라 게임 웹사이트
Unlike other types of cancer therapies, CAR T is a one-time treatment, officials said. The T cells remain in the body and, if the cancer comes back, the cells reactivate to attack the tumors.
바카라 게임 웹사이트These T cells go on to kill hundreds to thousands of tumor cells; the nickname for these cells is 바카라 게임 웹사이트serial killers,바카라 게임 웹사이트바카라 게임 웹사이트 said Dr. Adam Asch, deputy director of the Stephenson Cancer Center and chief of the Division of Medical Oncology and Hematology.
Using the immune system to fight cancer has been the holy grail for oncologists, Asch said.
바카라 게임 웹사이트The research data that led to the approval of CAR T has been extraordinary,바카라 게임 웹사이트 Asch said. 바카라 게임 웹사이트This therapy appears to be long-lasting in a high percentage of these patients.바카라 게임 웹사이트
According to officials, clinical trials are underway studying the effectiveness of CAR T in treating other blood cancers, including multiple myeloma, as well as solid tumors. Another trial will study the effectiveness of CAR T as compared to transplant; CAR T potentially could move ahead of transplant as a treatment because of its ability to use the patient바카라 게임 웹사이트s own immune system rather than someone else바카라 게임 웹사이트s. The Stephenson Cancer Center will be participating in several such clinical trials.